Micro AM for Drug-delivery Microneedles    Bio Resin

Microneedle and its arrays are emerging miniaturized medical devices for painless transdermal drug delivery, have been applied and promoted in consumer markets such as drug therapy, beauty spot removal, and cosmetic hair transplantation.

3D micro-nano fabrication technology has high design freedom and high-precision printing capability, which can be used to produce micro-needles with precise shapes, even micro-needle arrays with complex designs or customized materials. It can be applied in rapid prototyping, master production, and small batch production, enabling novel microneedle designs to be realized for preclinical and clinical trial assessments.

Why Micro 3D Printing 
The geometric shape of micro-needles has a crucial impact on their performance and efficacy, which is vital for their effective application in clinical trials. Advanced and versatile micro fabrication capabilities, especially in materials, resolution, shape accuracy, and printing speed, are required for innovative and challenging designs.

With the help of micro fabrication, below challenge which limits the design with traditional micro manufacturing can be tackled:

• Structure with high ratio of height vs width 
• Micro-needle array with variable periodicity and spatial distribution
• Solid and hollow micro-needles with symmetric and free shapes

Microneedles printed need to have good mechanical properties and biocompatibility to meet safety requirements for their applications. The material selection, structural design, and corresponding preparation techniques of microneedles are directly related to their effectiveness. Generally, the smoother the surface of microneedles, the better they can exhibit the advantages of safety, painlessness, and quantitative drug release.

We are able to print microneedles with 1mm height, minimum pinpoint structure of 15micron.